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KMID : 0816120000030010105
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2000 Volume.3 No. 1 p.105 ~ p.109
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Hepatocellular Carcinoma Following Vertical Transmission of Hepatitis B Virus in a Child with X-linked Agammaglobulinemia
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Oh Jong-Gon
Kook Hoon
Hwang Tai-Ju
Choi Young-Youn
Woo Young-Jong
Ma Jae-Sook
Seo Jong-Jin
Kim Byung-Ju
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Abstract
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X-linked agammaglobulinemia (XLA) is a primary inherited B-cell immunodeficiency.
The prevalence of neoplastic disease in patients with XLA is approximatedly 0.7%. The
most frequent tumor is lymphoreticular malignancy. We report a case of hepatocellular
carcinoma (HCC) in a 13-year-old boy with XLA, after probable maternal transmission
of hepatitis B virus. The authors consider that the vertical transmission of hepatitis B
virus might play an important role in the development of HCC in a child with XLA
who could not eliminate hepatitis B virus effectively.
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KEYWORD
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X-linked agammaglobulinemia, Hepatocellular carcinoma, Child, Hepatitis B,
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